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These inhibitory effects are observed both when probiotics are present as live cells and when only their secreted metabolites (postbiotics) are applied, indicating that soluble molecules alone can mediate a significant portion of the anti- Candida activity (Matsubara et al., 2016

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These neuroimmune responses disrupt the TJ and endothelial cell membranes, allowing the BBB to continuously break down and increase its leakage

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